Effects of an Endocrine Disruptor on Male Reproductive Organs.
نویسندگان
چکیده
منابع مشابه
Effects of an Endocrine Disruptor on Male Reproductive Organs
A 5-day Hershberger assay, a 20-day pubertal male assay, a one-month oral administration study and a reproductive toxicity study were carried out using an antiandrogenic chemical, flutamide (FL). The effects of FL were as follows: weight decrease in male reproductive organs such as the prostate and seminal vesicles were observed at ≥0.6 mg/kg/day as the most sensitive parameter in the Hershberg...
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The current study was designed to examine the actions of a model endocrine disruptor on embryonic testis development and male fertility. Pregnant rats (F0) that received a transient embryonic exposure to an environmental endocrine disruptor, vinclozolin, had male offspring (F1) with reduced spermatogenic capacity. The reduced spermatogenetic capacity observed in the F1 male offspring was transm...
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Exposure to pesticides could be one of the contributing cause to the falling sperm counts and rising levels of male infertility. Adverse effects of pesticides in the environment first received widespread attention in the 1960s. However, only recently it has been postulated that long term, low exposure of these chemicals are increasingly linked to human health effects such as immuno-suppression,...
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ژورنال
عنوان ژورنال: Journal of Toxicologic Pathology
سال: 2001
ISSN: 0914-9198,1881-915X
DOI: 10.1293/tox.14.79